Symbol
| DACT3
| contributors: mct - updated : 20-06-2012
|
HGNC name
| dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
|
HGNC id
| 30745
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
| loss of function
|
transcriptionally repressed in colorectal cancer | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | digestive | colon | |
potential strategy for therapeutic control of Wnt/beta-catenin signaling in colorectal cancer |
| | | |
| adult Dapper3-/- mice exhibited a mild reduction in body weight compared with their wild-type littermates, suggesting a functional role of Dapper3 in postnatal growth |