Symbol
| TRIM65
| contributors: mct - updated : 21-11-2018
|
HGNC name
| tripartite motif-containing 65
|
HGNC id
| 27316
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
combinatory inhibition of TRIM65 and MDM2 in lung cancer cells | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| overexpression of TRIM65 has an essential oncogenic role via ubiquitination of ANXA2 in urothelial carcinoma of the bladder pathogenesis, and could be used as a novel prognostic marker (P%ID: 30075204) | Therapy target
|
System | Type | Disorder | Pubmed |
cancer | urinary | | |
overexpression of TRIM65 could be used therapeutic target for urothelial carcinoma of the bladder |
| | |