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FLASH GENE
Symbol TRIM65 contributors: mct - updated : 21-11-2018
HGNC name tripartite motif-containing 65
HGNC id 27316
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
combinatory inhibition of TRIM65 and MDM2 in lung cancer cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • overexpression of TRIM65 has an essential oncogenic role via ubiquitination of ANXA2 in urothelial carcinoma of the bladder pathogenesis, and could be used as a novel prognostic marker (P%ID: 30075204)
  • Therapy target
    SystemTypeDisorderPubmed
    cancerurinary 
    overexpression of TRIM65 could be used therapeutic target for urothelial carcinoma of the bladder
    ANIMAL & CELL MODELS