Other morbid association(s)
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Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
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constitutional
|  
|  
|  
| loss of function
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known to mediate endoplasmic reticulum (ER) calcium release, as well as loss of ITPR2, necessary for mitochondrial calcium uptake, enable escape from oncogene-induced senescence (OIS) | constitutional
|  
| deletion
|  
|  
|
vascular endothelial deletion of MCU and MCUR1 impaired mitochondrial bioenergetics, cell proliferation, and migration but elicited autophagy | |