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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CACUL1

contributors: mct - updated : 05-04-2018

HGNC name	CDK2-associated, cullin domain 1
HGNC id	23727

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   expression level of CACUL1 in the hippocampus of Alzheimer disease patients was significantly lower than that of normal controls

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive prostate CACUL1 impairs KDM1A-mediated activation of AR, thereby implicating it as a potential antitumor target in prostate carcinoma

ANIMAL & CELL MODELS