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FLASH GENE

Symbol

ERRFI1

contributors: mct/np - updated : 10-04-2019

HGNC name	ERBB receptor feedback inhibitor 1
HGNC id	18185

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in ERBB2-amplified breast carcinomas constitutional     --over   in osteoarthritic cartilage tumoral     --low   in endometrial cancers (Jeong 2009)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     targeting of EFFRI1 in EGFR-low cancer as a promising therapeutic approach

ANIMAL & CELL MODELS