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FLASH GENE
Symbol PREX2 contributors: mct/npt - updated : 24-05-2016
HGNC name phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
HGNC id 22950
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral somatic mutation      
somatic mutations generate truncated or variant proteins that gain oncogenic activity in melanoma cells
Susceptibility
Variant & Polymorphism
Candidate gene
  • is a candidate melanoma gene whose amplifications, rearrangements or mutations appeared to undergo positive selection in human melanoma genesis
  • Marker
    Therapy target
    ANIMAL & CELL MODELS