Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ALKBH5 contributors: mct - updated : 03-09-2016
HGNC name alkB, alkylation repair homolog 5 (E. coli)
HGNC id 25996
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
METTL14, YTHDF3 and ALKBH5 were downregulated in Colorectal cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Alkbh5-deficient male mice have increased N(6)-methyladenosine (m(6)A) in mRNA and are characterized by impaired fertility resulting from apoptosis that affects meiotic metaphase-stage spermatocytes