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FLASH GENE
Symbol PKN3 contributors: mct - updated : 13-06-2017
HGNC name protein kinase N3
HGNC id 17999
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
impairs actin and adherens junctions dynamics and attenuates endothelial cell activation
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
PKN3-RHOC complex represents an attractive therapeutic target in late-stage malignancies
ANIMAL & CELL MODELS