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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CCDC80

contributors: mct - updated : 20-04-2013

HGNC name	coiled-coil domain containing 80
HGNC id	30649

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in colon and pancreatic cancer cell lines as well as in most colorectal cancer specimens

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	up-regulated in brown adipose tissue of mildly obese bombesin receptor subtype-3 (BRS-3-/-) mice
	mice lacking Ccdc80 showed increased sensitivity to diet-induced hyperglycemia and glucose intolerance while displaying reduced glucose-stimulated insulin secretion