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FLASH GENE

Symbol

ARHGAP29

contributors: mct - updated : 16-07-2018

HGNC name	Rho GTPase activating protein 29
HGNC id	30207

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional germinal mutation       associated with an increased risk for Nonsyndromic cleft lip and/or palate (NSCL/P) tumoral     --over   is correlated with shortened survival of gastric cancer patients

Susceptibility

to non-syndromic cleft lip with or without cleft palate

Variant & Polymorphism other	common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting

Candidate gene	is a strong candidate tumor suppressor gene in Mantle cell lymphoma (MCL)
Marker
Therapy target

ANIMAL & CELL MODELS