Symbol
| OSMR
| contributors: mct - updated : 11-03-2020
|
HGNC name
| oncostatin M receptor
|
HGNC id
| 8507
|
corresponding disease(s)
|
FPLCA
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
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constitutional
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silencing inhibits the activation of the JAK/STAT3 signaling pathway, thereby suppressing the development of chronic autoimmune urticaria (CAU) | tumoral
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| --over
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in advanced cervical squamous cell carcinoma (SCC) | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| may serve as a biomarker candidate gene to predict prognosis of bladder cancer | Therapy target
| | |
| mice, lacking the OSM receptor (Osmr) in adipocytes (OsmrFKO mice), exhibit derangements in adipose tissue, insulin sensitivity, and immune cell balance |