Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ECRG4 contributors: mct/npt - updated : 10-03-2010
HGNC name chromosome 2 open reading frame 40
HGNC id 24642
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by CpG island hypermethylation in esophageal squamous cell carcinoma (Yue 2003)
constitutional     --low  
during chondrocyte dedifferentiation and cartilage destruction (Huh 2009)
Susceptibility
Variant & Polymorphism
Candidate gene
  • candidate tumor suppressor gene in ESCC (esophageal squamous cell carcinoma), and is a candidate prognostic marker for ESCC (Li 2009)
  • marker of differentiated articular chondrocyte and cartilage destruction, with a capacity to inhibit proliferation of differentiated chondrocytes (Huh 2009)
  • Marker
    Therapy target
    ANIMAL & CELL MODELS