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FLASH GENE
Symbol NXNL1 contributors: mct - updated : 11-12-2015
HGNC name nucleoredoxin-like 1
HGNC id 25179
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
neurosensorialvisualretina
administration of NXNL1 would maintain cones and central vision in most patients suffering from RP
neurosensorialvisual 
therapeutic potential for the treatment of retinitis pigmentosa
ANIMAL & CELL MODELS
in the rd1 mouse, a model of RP, the expression by rods of the trophic factor NXNL1 is lost through their degeneration, but the reduction in its expression by bipolar cells results from a downregulation of its expression