Symbol
| DOCK5
| contributors: mct - updated : 11-01-2017
|
HGNC name
| dedicator of cytokinesis 5
|
HGNC id
| 23476
|
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
osteoarticular | bone | ostéoporosis | |
pharmacological inhibition of DOCK5 is a novel therapeutic route for fighting osteolytic diseases while preserving bone formation |
| | | |
| adult Dock5(-/-) mice have increased trabecular bone mass, and also have normal hypertrophic cartilage and cartilage trabecular network | |
Dock5-deficient mice exhibit resistance to systemic and cutaneous anaphylaxis |