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FLASH GENE
Symbol TPCN2 contributors: shn/mct - updated : 27-12-2017
HGNC name two pore segment channel 2
HGNC id 20820
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in oral cancer
Susceptibility
Variant & Polymorphism SNP skin and hair pigmentation
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • absence of intracellular ion channels Tpcn1 and Tpcn2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue