Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol NEIL2 contributors: mct/npt - updated : 18-12-2014
HGNC name nei like 2 (E. coli)
HGNC id 18956
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional   deletion    
in congenital heart disease
Susceptibility
  • to familial colorectal cancer
  • to lung cancer development
  • Variant & Polymorphism other
  • missense variants increasing the risk of colorectal cancer
  • decreased DNA repair capacity of the R257L variant can induce mutations that lead to lung cancer development
  • Candidate gene
  • polymorphisms of the NEIL2 gene may be markers for risk and progression of squamous cell carcinoma of the oral cavity and oropharynx, particularly in patients with oropharyngeal cancer (Zhai 2008)
  • Marker
    Therapy target
    ANIMAL & CELL MODELS