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FLASH GENE
Symbol ARID4B contributors: mct - updated : 21-08-2010
HGNC name AT rich interactive domain 4B (RBP1- like)
HGNC id 15550
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in cancer cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
heterozygous deficiency for Rbbp1l1/Arid4b altered epigenetic modifications at the Prader-Willi syndrome -IC with reduced trimethylation of histone H4K20 and H3K9 and reduced DNA methylation, changing the maternal allele toward a more paternal epigenotype (Wu 2006)