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FLASH GENE
Symbol CCR5 contributors: mct - updated : 07-07-2010
HGNC name chemokine (C-C motif) receptor 5
HGNC id 1606
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
  • to AIDS lymphoma
  • to HIV disease progression, resistance or non progressive infections
  • to West Nile virus (Omim 610379)
  • to juvenile idiopathic arthritis (JIA)
  • Variant & Polymorphism other
  • reduced risk of AIDS lymphoma with the CCR5-delta 32 mutation
  • CCR5Delta32 is a functional variant, significantly associated with protection from developing JIA
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS