Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ANXA2 contributors: mct - updated : 15-06-2016
HGNC name annexin A2
HGNC id 537
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in small cell lung carcinoma
tumoral     --over  
in the clear-cell renal cell carcinoma, significant associations with a higher stage, a higher nuclear grade
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • MYH7, IGFBP7, ANXA2, and DES are all excellent candidate plasma biomarkers of heart failure
  • may be new prognostic marker of metastatic pancreatic ductal adenocarcinoma (PDA)
  • Therapy target
    SystemTypeDisorderPubmed
    cancerbrainglioma/neuroblstoma
    inhibition of annexin A2 expression in glioma cells could become a new target for glioma therapy
    allergyasthm 
    targeting ANXA2-mediated signaling may provide a novel therapeutic approach to the treatment of airway inflammation in diseases such as chronic asthma
    cancerendocrinepancreas
    may be new and prognostic marker of metastatic pancreatic ductal adenocarcinoma (PDA)
    ANIMAL & CELL MODELS