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FLASH GENE
Symbol SLC39A6 contributors: mct - updated : 12-11-2021
HGNC name solute carrier family 39 (zinc transporter), member 6
HGNC id 18607
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in oestrogen-positive breast cancer with metastasis
constitutional       gain of function
strongly upregulated early during T cell activation
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • could serve as an early detector of high-risk subjects and prognostic biomarker in Esophageal squamous cell carcinoma (ESCC)
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveoesophagus
    targeting of SLC39A6 might be a potential therapeutic strategy for blocking ESCC
    ANIMAL & CELL MODELS