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FLASH GENE
Symbol TGFA contributors: mct/npt/pgu - updated : 02-10-2023
HGNC name transforming growth factor, alpha
HGNC id 11765
ASSOCIATED DISORDERS
corresponding disease(s) OFC2
Susceptibility
  • to cleft lip with/without cleft palate
  • to tooth agenesis
  • Variant & Polymorphism other variants and haplotypes are associated with tooth agenesis
    Candidate gene
    Marker could be used as blast cell biomarker in diagnostic haematopathology
    Therapy target
    SystemTypeDisorderPubmed
    cancerhemopathy 
    TGFA immunohistochemistry may be of use in identifying a therapeutic target
    ANIMAL & CELL MODELS
    highly,in the epithelial tissue of the medial edge of the palatal shelves at the time of shelf fusion in mice