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FLASH GENE
Symbol SLC22A16 contributors: mct/npt - updated : 30-04-2010
HGNC name solute carrier family 22 (organic cation/carnitine transporter), member 16
HGNC id 20302
ASSOCIATED DISORDERS
corresponding disease(s) MAFD17
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in endometrium during the normal secretory phase, but its level was significantly reduced in the proliferative phase
tumoral     --over  
in endometrial cancer in the presence of progesterone
tumoral     --over  
in testicular cancer cells (Aouida 2010)
Susceptibility for bipolar disorder type I
Variant & Polymorphism
Candidate gene
Marker
Therapy target use progestins to increase the response of endometrioid endometrial carcinoma with SLC22A16 expression to adriamycin-based chemotherapeutic regimens
ANIMAL & CELL MODELS