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FLASH GENE
Symbol UPF2 contributors: mct - updated : 03-10-2017
HGNC name UPF2 regulator of nonsense transcripts homolog (yeast)
HGNC id 17854
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • ablation of Upf2, which encodes a core NMD factor, in murine embryonic Sertoli cells (SCs) leads to severe testicular atrophy and male sterility owing to rapid depletion of both SCs and germ cells during prepubertal testicular development