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FLASH GENE

Symbol

SEC31A

contributors: mct - updated : 29-06-2018

HGNC name	SEC31 homolog A (S. cerevisiae)
HGNC id	17052

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral fusion translocation     fused with ALK, in a translocation t(2;4)(p23;q21), in an intraabdominal inflammatory myofibroblastic tumor tumoral fusion       SEC31A-ALK, in lung carcinoma

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	SEC31A-ALK fusion transcript in clinical NSCLC, could be a novel diagnostic and therapeutic target for patients with non-small cell lung carcinoma (NSCLC)
Therapy target

ANIMAL & CELL MODELS