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FLASH GENE
Symbol SEC31A contributors: mct - updated : 29-06-2018
HGNC name SEC31 homolog A (S. cerevisiae)
HGNC id 17052
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral fusion translocation    
fused with ALK, in a translocation t(2;4)(p23;q21), in an intraabdominal inflammatory myofibroblastic tumor
tumoral fusion      
SEC31A-ALK, in lung carcinoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • SEC31A-ALK fusion transcript in clinical NSCLC, could be a novel diagnostic and therapeutic target for patients with non-small cell lung carcinoma (NSCLC)
  • Therapy target
    ANIMAL & CELL MODELS