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FLASH GENE
Symbol ANTXR1 contributors: mct - updated : 05-06-2013
HGNC name anthrax toxin receptor 1
HGNC id 21014
ASSOCIATED DISORDERS
corresponding disease(s) GAPOS
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in tumor endothelial cells
constitutional germinal mutation      
in infantile hemangiomas, mutations resulting in increased interactions among KDR, ANTXR1, and beta 1 integrin proteins and in inhibition of integrin activity
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerangiogenesis 
ANTXR1 targeting may allow selective inhibition of pathological angiogenesis
ANIMAL & CELL MODELS