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FLASH GENE
Symbol BTG2 contributors: mct/npt/pgu - updated : 08-11-2016
HGNC name BTG family, member 2
HGNC id 1131
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   LOH    
in carcinogenesis of thymus, prostate, kidney, and liver
tumoral     --low  
in prostate cancer
Susceptibility to Graves disease
Variant & Polymorphism SNP
  • SNPs rs12136280, rs6663606, and rs17534202 in BTG2 were associated with Graves disease
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerdigestivestomach
    in gastric cancer, BTG2 could be thought as a tumor-inhibiting gene in some distance, so the gene could be a potential target of gene therapy
    cancerskin 
    novel therapeutic strategies and agents targeting BTG2 may be potential treatments for skin cancer
    ANIMAL & CELL MODELS