Symbol
| ARHGAP15
| contributors: mct - updated : 28-12-2022
|
HGNC name
| Rho GTPase activating protein 15
|
HGNC id
| 21030
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
in lung cancer tissues and cells | |
Susceptibility
|
to chondromalacia |
Variant & Polymorphism
SNP
| rs144449054 in the ARHGAP15 associated with chondromalacia |
|
|
Candidate gene
Marker
| ARHGAP15 immunoreactivity is considered a potent prognostic factor in human breast carcinomas | Therapy target
|
System | Type | Disorder | Pubmed |
immunology | infectious | | |
ARHGAP15 targeting might be beneficial in specific pathologic settings like severe sepsis |
| | |
| Adult ArhGAP15-/- mice showed defective hippocampus-dependent functions such as working and associative memories |