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FLASH GENE
Symbol ARHGAP15 contributors: mct - updated : 28-12-2022
HGNC name Rho GTPase activating protein 15
HGNC id 21030
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in lung cancer tissues and cells
Susceptibility to chondromalacia
Variant & Polymorphism SNP
  • rs144449054 in the ARHGAP15 associated with chondromalacia
  • Candidate gene
    Marker
  • ARHGAP15 immunoreactivity is considered a potent prognostic factor in human breast carcinomas
  • Therapy target
    SystemTypeDisorderPubmed
    immunologyinfectious 
    ARHGAP15 targeting might be beneficial in specific pathologic settings like severe sepsis
    ANIMAL & CELL MODELS
  • Adult ArhGAP15-/- mice showed defective hippocampus-dependent functions such as working and associative memories