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FLASH GENE
Symbol CMKLR1 contributors: mct/npt/pgu - updated : 10-07-2017
HGNC name chemokine-like receptor 1
HGNC id 2121
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in psoriasis and atopic dermatitis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • mesenchymal stem cell (MSC) from Cmklr1 knockout (-/-) mice exhibited similar dependency on Notch signaling to maintain osteoblastogenic differentiation
  • Cmklr1 null mice have a subtle skeletal muscle deficit beginning from embryonic life that persists during postnatal life