Symbol
| NECTIN4
| contributors: mct - updated : 20-12-2016
|
HGNC name
| nectin cell adhesion molecule 4
|
HGNC id
| 19688
|
corresponding disease(s)
|
EDCS2
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
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tumoral
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| --over
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transactivated in a majority of NSCLC (Takano 2009) | tumoral
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histological and serological tumor-associated marker for breast carcinoma (Fabre-Lafay 2007) | |
Variant & Polymorphism
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Candidate gene
Marker
Therapy target
| high level of expression is associated with poor prognosis in NSCLC (Takano 2009) | |
might play a significant role in lung carcinogenesis and should be a new candidate serum and tissue biomarker as well as a therapeutic target (Takano 2009) | |
marker of disease progression and levels correlating with the number of metastasis in breast carcinomas (Fabre-Lafay 2007) |
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