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FLASH GENE
Symbol TRIP13 contributors: mct/npt - updated : 01-06-2018
HGNC name thyroid hormone receptor interactor 13
HGNC id 12307
ASSOCIATED DISORDERS
corresponding disease(s) OOMD5 , MVA3
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in early stages of non-small cell lung cancer (Kang 2008)
tumoral     --over  
promote lung adenocarcinoma tumor progression
Susceptibility
Variant & Polymorphism
Candidate gene
Marker potential biomarker for lung adenocarcinoma
Therapy target
SystemTypeDisorderPubmed
cancerlung 
therapeutic target for lung adenocarcinoma
cancerdigestivecolon
could be a potential target for CRC treatment
ANIMAL & CELL MODELS
  • both male and female Trip13-knockout mice are infertile