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FLASH GENE
Symbol SDCBP contributors: mct/pgu - updated : 23-08-2016
HGNC name syndecan binding protein (syntenin)
HGNC id 10662
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by RNA interference could provide a means of inhibiting tumor invasion and possibly metastasis in different cancers
tumoral     --over  
in melanoma, and breast and gastric cancer cells (
tumoral     --over  
in high-grade astrocytomas
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
PDZ domains of SDCBP is a promising potential therapeutic targets for intervening in a decisive component of cancer progression, namely, metastatic tumor spread
cancer  
a potential cancer biomarker and drug target
ANIMAL & CELL MODELS