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FLASH GENE
Symbol CDK1 contributors: mct/ - updated : 27-12-2019
HGNC name cyclin-dependent kinase 1
HGNC id 1722
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
cells lacking CDK1 cannot proliferate but instead enter a senescent state and survive in culture medium
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • reliable molecular biomarker for the diagnosis of prostate carcinoma
  • Therapy target
    SystemTypeDisorderPubmed
    cancer  
    potential of CDK1 inhibitors in cancer therapy
    ANIMAL & CELL MODELS