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FLASH GENE
Symbol PAPPA2 contributors: mct/npt/pgu - updated : 24-09-2013
HGNC name pappalysin 2
HGNC id 14615
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in placentas of preeclampsia and HELLP syndrome
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • has potential as a biomarker for pre-eclampsia
  • may be a useful biomarker of placental dysfunction 8)
  • Therapy target
    ANIMAL & CELL MODELS
  • adult femur and body length were also reduced in Papp-A2 KO mice, but without significant effects on bone mineral density