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FLASH GENE

Symbol

TMPO

contributors: mct - updated : 28-09-2016

HGNC name	thymopoietin
HGNC id	11875

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CMD1T

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional germinal mutation       of the LAP2 alpha isoform, in the LMNA binding region, in familial dilated cardiomyopathy

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	LAP2beta may have utility for diagnostics and therapeutics in digestive tract cancers
Therapy target

ANIMAL & CELL MODELS

in cardiac tissue, deletion of Tmpo caused systolic dysfunction in young mice with an increased susceptibility for fibrosis in old animals