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FLASH GENE
Symbol NEK9 contributors: mct/pgu - updated : 01-06-2016
HGNC name NIMA (never in mitosis gene a)- related kinase 9
HGNC id 18591
ASSOCIATED DISORDERS
corresponding disease(s) LCCSR
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
overexpressed in primary breast tumors
constitutional somatic mutation      
in NC (Nevus Comedonicus) disrupt normal follicular differentiation
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
NEK9 inhibition represents a novel anti-cancer strategy by induction of mitotic catastrophe via impairment of spindle dynamics, cytokinesis and mitotic checkpoint control
ANIMAL & CELL MODELS