Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

GPR17

contributors: mct/npt - updated : 19-12-2013

HGNC name	G protein-coupled receptor 17
HGNC id	4471

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in demyelinating lesions in the CNS constitutional     --over   in multiple sclerosis plaques

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed immunology autoimmune multiple sclerosis inhibiting GPR17 emerges as therapeutic strategy to relieve the oligodendrocyte maturation block and promote myelin repair in MS neurology neurodegenerative   may serve as a potential therapeutic target for CNS myelin repair neurology acquired   target for neurorepair and are particularly relevant to setting up new therapies for traumatic brain injury (TBI) patients

ANIMAL & CELL MODELS

Gpr17 knockout mice showed early onset of oligodendrocyte myelination