Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol FDPS contributors: mct/npt - updated : 08-06-2009
HGNC name farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
HGNC id 3631
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
in the hepatic tissue of patients with peroxisomal disorders such as Zellweger disease and neonatal adrenoleukodystrophy (Romanelli 2009)
Susceptibility to lower BMD in postmenopausal Caucasian women
Variant & Polymorphism SNP (rs2297480) may be a genetic marker for lower BMD in postmenopausal Caucasian women (Levy 2007)
Candidate gene
Marker
Therapy target selective target of alendronate in the mevalonate pathway (Bergstrom 2000)
ANIMAL & CELL MODELS