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FLASH GENE

Symbol

COTL1

contributors: mct - updated : 28-08-2010

HGNC name	coactosin-like 1 (Dictyostelium)
HGNC id	18304

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to autoimmune disorders

Variant & Polymorphism other	c.-1124G>T and c. 484G>A polymorphisms of the COTL1 gene might be associated with the genetic susceptibility of autoimmune disorders

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed immunology autoimmune   COTL1/ALOX5 as therapy to reduce leukotriene formation in the cell

ANIMAL & CELL MODELS