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FLASH GENE
Symbol HSPA8 contributors: mct/ - updated : 12-09-2016
HGNC name heat shock 70kDa protein 8
HGNC id 5241
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in gastric cancer
constitutional     --low  
of HSPA8 and HSPA9 was observed in Alzheimer disease across the three brain regions compared to the controls, suggesting their participation in AD pathogenesis
Susceptibility
Variant & Polymorphism
Candidate gene
  • novel molecular basis for the protective effect of HSPA8 in tauopathies
  • Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerangiogenesis 
    may provide the basis for the development of new therapeutic strategies for angiogenesis
    neurologyepilepsy 
    could be a potential therapeutic target of Lafora disease
    ANIMAL & CELL MODELS