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FLASH GENE
Symbol NUF2 contributors: mct/npt - updated : 01/10/2008
HGNC name NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
HGNC id 14621
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in lung cancer
tumoral     --over  
in colorectal and gastric cancers (Kaneko 2009)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target suppression of NUF2 or NDC80 activity and/or inhibition of the NUF2-NDC80 complex formation could be a promising therapeutic target for treatment of lung cancers
ANIMAL & CELL MODELS