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FLASH GENE
Symbol CD177 contributors: mct - updated : 28-11-2017
HGNC name CD177 antigen
HGNC id 30072
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in neutrophils of patients with polycythemia vera and essential thrombocytemia
         
Alloimmunization to the neutrophil antigen NB1 (HNA-2a, CD177) can result in neonatal immune neutropenia and transfusion-related acute lung injury
constitutional     --over  
increased mRNA levels of both PRTN3 and CD177 in ANCA)-associated systemic vasculitis (AASV)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS