Symbol
| EGLN2
| contributors: mct/ - updated : 17-02-2014
|
HGNC name
| egl nine homolog 2 (C. elegans)
|
HGNC id
| 14660
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
is protective against colitis through decreased epithelial cell apoptosis and consequent enhancement of intestinal epithelial barrier function | tumoral
|  
|  
| --other
|  
|
dysregulation of EGLN2 facilitated prostate cancer growth both in cells | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| pharmacological inhibition may provide a useful means to protect muscle, and potentially other organs, from ischemic injury |
|
System | Type | Disorder | Pubmed |
immunology | inflammatory | | |
targeted EGLN2 inhibition may represent a new therapeutic approach in inflammatory bowel disease |
| | |