Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EGLN2 contributors: mct/ - updated : 17-02-2014
HGNC name egl nine homolog 2 (C. elegans)
HGNC id 14660
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
is protective against colitis through decreased epithelial cell apoptosis and consequent enhancement of intestinal epithelial barrier function
tumoral     --other  
dysregulation of EGLN2 facilitated prostate cancer growth both in cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target pharmacological inhibition may provide a useful means to protect muscle, and potentially other organs, from ischemic injury
SystemTypeDisorderPubmed
immunologyinflammatory 
targeted EGLN2 inhibition may represent a new therapeutic approach in inflammatory bowel disease
ANIMAL & CELL MODELS