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FLASH GENE

Symbol

TREM1

contributors: mct - updated : 29-06-2012

HGNC name	triggering receptor expressed on myeloid cells 1
HGNC id	17760

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in infectious exacerbations of chronic obstructive pulmonary disease constitutional     --over   in biological fluids and tissues infected by Gram (+) and Gram (-) bacteria and fungi, amplifies the production of pro-inflammatory cytokines and chemokines constitutional     --over   on monocytes is associated with both infectious and noninfectious inflammatory processes

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	serum TREM1 level could be a potential marker for the assessment of disease activity of intestinal Behcet disease
Therapy target

ANIMAL & CELL MODELS