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FLASH GENE
Symbol FKBP8 contributors: mct/npt/pgu - updated : 20-04-2017
HGNC name FK506 binding protein 8, 38kDa
HGNC id 3724
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in breast, colon, liver, lung, lymph node, prostate, and stomach cancers
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
N-terminal domain of FKBP38 could have therapeutic potential for the metastatic cancer overexpressing PRL family
ANIMAL & CELL MODELS
  • mice deficient in Fkbp38 die soon after birth manifesting a defect in neural tube closure that results in part from unrestrained apoptosis