Symbol
| EMSY
| contributors: mct - updated : 02-12-2021
|
HGNC name
| EMSY transcriptional repressor, BRCA2 interacting
|
HGNC id
| 18071
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
| amplification
|  
|  
|
in sporadic breast cancer and higher-grade ovarian cancer with poor prognosis | tumoral
|  
|  
| --over
|  
|
in various sporadic cancers  | |
Susceptibility
|
to prostate cancer and prostate cancer death |
Variant & Polymorphism
SNP
| the most significant association with prostate cancer and death is at rs12277366  |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | reproductive | ovary |  |
might be a promising target for the treatment of ovarian cancer |
| | | |