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FLASH GENE
Symbol STAP1 contributors: mct/npt - updated : 22-04-2009
HGNC name signal transducing adaptor family member 1
HGNC id 24133
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target potential candidate for therapeutic modulation of microglia activity and molecular target for limiting microglia activation in neurodegenerative disorders(Stoecker 2009)
ANIMAL & CELL MODELS
STAP-1-deficient mice will be a valuable tool to further study the in vivo role of this adaptor protein and its involvement in molecular mechanisms of microglia homeostasis (Stoecker 2009)