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FLASH GENE
Symbol EIF4A2 contributors: mct - updated : 02-09-2020
HGNC name eukaryotic translation initiation factor 4A, isoform 2
HGNC id 3284
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
non-small-cell lung cancer (NSCLC) patients with low EIF4A2 expression survived shorter than those with high EIF4A2 expression
tumoral     --over  
high expression levels of EIF4A2 are associated with a poor prognosis in esophageal squamous cell carcinoma (ESCC)
Susceptibility
Variant & Polymorphism
Candidate gene to type 2 diabetes in French families
Marker
  • could be served as a potential prognostic marker for patients with non-small-cell lung cancer (NSCLC)
  • may be used as a potential prognostic indicator in patients with ESCC
  • Therapy target
    ANIMAL & CELL MODELS