Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CLN3 contributors: mct/npt/pgu - updated : 25-10-2017
HGNC name ceroid-lipofuscinosis, neuronal 3
HGNC id 2074
ASSOCIATED DISORDERS
corresponding disease(s) CLN3
related resource Neuronal Ceroid Lipofuscinoses
Neuronal Ceroid Lipofuscinoses
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
seems to cause neurodegeneration via a process that does not require apoptosis
constitutional     --over  
is sufficient to confer increased resistance to oxidative stress
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Cln3 deficient mouse model
  • canine model of juvenile Batten disease