Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PPFIA1 contributors: mct/npt - updated : 27-02-2024
HGNC name protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
HGNC id 9245
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in head and neck squamous cell carcinoma
tumoral   amplification    
in breast cancer, coamplified with CCND1 (Dancau 2010)
tumoral     --over  
higher in colorectal cancers (CRCs) tissue samples than in normal colon tissue
tumoral     --over  
in breast cancer was associated with worse prognosis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
status of PPFIA1 may assist in predicting drug responses in cancer cells in a context-dependent manner
ANIMAL & CELL MODELS