Symbol
| MAPK10
| contributors: mct/pgu - updated : 20-06-2015
|
HGNC name
| mitogen-activated protein kinase 10
|
HGNC id
| 6872
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
| deletion
|  
|  
|
in pharmacoresistant epileptic encephalopathy type Lennox-Gastaut | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| PPP2CB, MAPK10, RAC3 were independent prognostic factors for bladder cancer (BLCA) | Therapy target
| | |
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
| deletion
|  
|  
|
in pharmacoresistant epileptic encephalopathy type Lennox-Gastaut | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| PPP2CB, MAPK10, RAC3 were independent prognostic factors for bladder cancer (BLCA) | Therapy target
| | |
| Jnk3 null mice showed an increase in pik3cb transcript and protein, together with an increase in PI3K activity and phosphorylation of AKT |